Pseudorotation of Natural and Chemically Modified Biological Phosphoranes: Implications for RNA Catalysis
نویسندگان
چکیده
منابع مشابه
Pseudorotation barriers of biological oxyphosphoranes: a challenge for simulations of ribozyme catalysis.
Pseudorotation reactions of biologically relevant oxyphosphoranes were studied by using density functional and continuum solvation methods. A series of 16 pseudorotation reactions involving acyclic and cyclic oxyphosphoranes in neutral and monoanionic (singly deprotonated) forms were studied, in addition to pseudorotation of PF5. The effect of solvent was treated by using three different solvat...
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Atmospheric pressure (AP) MALDI has been combined with Fourier transform mass spectrometry (FTMS) to obtain the unambiguous characterization of RNA samples modified by solvent accessibility reagents used in structural studies of RNA and protein-RNA complexes. The formation of cation adducts typical of MS analysis of nucleic acids was effectively reduced by extensive washing of the anionic analy...
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ژورنال
عنوان ژورنال: ChemPhysChem
سال: 2004
ISSN: 1439-4235,1439-7641
DOI: 10.1002/cphc.200490049